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The Human Phenotype Project

About Project 10K

A long-term observational study designed to predict disease years before it appears — combining medicine, biology and computer science.

What we do

Project 10K follows thousands of participants in Israel over many years, collecting deep data on lifestyle, body and health through questionnaires and advanced medical tests.

By tracking each person over time, we look for the earliest signals that link everyday exposures — diet, sleep, activity, microbiome — to the onset of disease.

Our purpose

Our goal is to develop methods that predict diseases years before they break out — shifting medicine from treatment toward prevention, personalized to each individual.

A study by the Weizmann Institute of Science, combining medicine, biology and computer science.

The science behind 10K

From thousands of measurements to early signals — three steps.

1
Deep phenotyping

Thousands of measurements per person — blood, genetics, gut microbiome, imaging, sleep and more.

2
AI models

Machine-learning models surface patterns across this data that humans can't see.

3
Predict early

Detect the earliest signals of disease — often years before symptoms appear.

Scientists & Partners

Researchers, physicians and data scientists behind the study — conducted at and in partnership with the Weizmann Institute of Science.

Prof. Eran Segal
Principal Investigator
Dr. Smadar Shilo
Physician-researcher
Dr. Adina Weinberger
Lab & operations lead
Dr. Ori Cohen
Researcher
Dr. Yeela Talmor
Cardiology research
Dr. Tal Ofek
Researcher
Hagai Rossman
Data scientist
Nastya Godneva
Data scientist
Weizmann Institute of Science
Project 10K is conducted at, and in partnership with, the Weizmann Institute of Science.