For Researchers

The Human Phenotype Project makes one of the world's most detailed health datasets available to the research community.

About the Cohort

A deeply-phenotyped cohort followed over time — built to let researchers ask new questions about the path from health to disease.

~13,500

Participants enrolled

10+

Data modalities

10 yrs

Planned follow-up

Each participant contributes thousands of measurements across clinical, molecular, imaging and behavioural domains, with repeat visits over the course of the study. The result is a longitudinal, multi-modal resource designed for discovery across the full health–disease continuum.

Cohort Profile & Methodology

How data is collected across each participant visit.

Clinical visits

Standardised in-person assessments and physical measurements at each follow-up.

Questionnaires

Lifestyle, diet, medical history and well-being surveys collected over time.

Blood & biomarkers

Comprehensive blood panels, metabolomics and other molecular assays.

Gut microbiome

Metagenomic sequencing of stool samples for microbial composition and function.

Continuous glucose

CGM monitoring capturing real-world glycaemic response over multiple days.

Imaging

Body composition, cardiac and other imaging modalities per protocol.

Sleep & activity

Wearable-derived sleep, heart rate and physical activity records.

Anthropometrics

Repeated body measurements tracked across the longitudinal follow-up.

Cohort profile & methodology

Full description of recruitment, protocols and data processing — downloadable PDF.

Download methodology →

Data Dictionary & Tools

Everything you need to explore the data and request access.

Data Dictionary

Browse every measured variable, with definitions, units and coverage.

Access Request

Apply for access to de-identified data for approved research projects.

Analysis Tools / API

Programmatic access and tooling to query and analyse the dataset.

Sample Datasets

Representative example data to evaluate structure before applying.

Publications

Peer-reviewed papers, all co-authored by Prof. Eran Segal.

20252024202320222021…2014

Deep phenotyping of health-disease continuum in the Human Phenotype Project

Reicher L., Shilo S., … Segal E. · Nature Medicine · 2025

Multimodal AI correlates of glucose spikes…

Carletti M., … Segal E. · Nature Medicine · 2025

Artificial intelligence in metabolic research

… Segal E. · Nature Metabolism · 2025

Precision nutrition for cardiometabolic diseases

… Segal E. · Nature Medicine · 2025

Clinical translation of microbiome research

Gilbert J. A., … · 2025

View all publications →

Collaboration

We welcome research collaborations that extend and enrich the dataset.

The Human Phenotype Project is conducted at the Weizmann Institute of Science. Research groups interested in joint analyses, linked sub-studies or shared methodology are invited to get in touch.

Propose a collaboration

Contact & Support

Questions about data access, applications or the dataset? The research team is here to help.

Contact the research team ↗